Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831633 | 0.98 | ALDH1A1 (0.48) | ALDH1A1HDAC8HDAC6HDAC1HTT | |
| SCHEMBL108064 | 0.98 | ALDH1A1 (0.48) | ALDH1A1HDAC8HDAC6HDAC1HTT | |
| SCHEMBL10492574 | 0.98 | ALDH1A1 (0.48) | ALDH1A1HDAC8HDAC6HDAC1HTT | |
| SCHEMBL9830384 | 0.96 | ALDH1A1 (0.50) | ALDH1A1HDAC8HDAC6HDAC1HTT | |
| SCHEMBL7672667 | 0.92 | NOTUM (0.44) | ALDH1A1HDAC8HDAC6HDAC1HTT | |
| SCHEMBL3938368 | 0.91 | ALDH1A1 (0.50) | ALDH1A1HDAC8HDAC6HDAC1HTT | |
| SCHEMBL31381836 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HDAC8TDP1POLBESR2 | |
| Cyanide SCHEMBL27694921 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HDAC8TDP1POLBESR2 | |
| SCHEMBL1087968 | 0.81 | NPC1 (0.51) | HDAC8HDAC6HDAC1HTTHDAC3 | |
| SCHEMBL11318751 | 0.80 | HDAC8 (0.47) | HDAC8HDAC6HDAC1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640596-B2 | Rubber polymer, graft copolymer, preparation methods therefor, and impact resistant and heat resistant resin composition | LG CHEM, LTD. (KR) | 2020-05-05 | — | — | US | claimed |