Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318771 | 1.00 | HDAC8 (0.47) | HDAC8HDAC6HDAC1KMT2ARAB9A | |
| SCHEMBL10492686 | 0.91 | HDAC8 (0.44) | HDAC8HDAC6HDAC1KMT2ARAB9A | |
| SCHEMBL10128976 | 0.90 | CYP19A1 (0.47) | HDAC8HDAC6HDAC1KMT2ARAB9A | |
| SCHEMBL13636754 | 0.88 | KMT2A (0.40) | HDAC8HDAC6HDAC1KMT2ARAB9A | |
| SCHEMBL12292323 | 0.88 | KMT2A (0.40) | HDAC8HDAC6HDAC1KMT2ARAB9A | |
| SCHEMBL4452066 | 0.86 | HTT (0.43) | HDAC8HDAC6HDAC1KMT2ARAB9A | |
| SCHEMBL1305304 | 0.85 | RELA (0.43) | HDAC8HDAC6HDAC1KMT2ARAB9A | |
| SCHEMBL1305302 | 0.85 | RELA (0.43) | HDAC8HDAC6HDAC1KMT2ARAB9A | |
| SCHEMBL6275125 | 0.84 | HDAC8 (0.52) | HDAC8HDAC6HDAC1KMT2ARAB9A | |
| SCHEMBL15260520 | 0.84 | HDAC8 (0.52) | HDAC8HDAC6HDAC1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293717-A | Process for preparing aldehydes and diols | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | claimed |
| US-3972944-A | BORON OXIDE, BORIC ACID OR BORATE AND VANADIUM OR MOLYBDENUM CONTAINING CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |