Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 11/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.32 |
| ▸ | CPN1 | P15169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091841 | 0.86 | ACACB (0.42) | ACACB | |
| SCHEMBL24368018 | 0.86 | ACACB (0.34) | ACACBITGB3ITGA2BANPEPERAP2 | |
| SCHEMBL16000112 | 0.84 | ACACB (0.38) | ACACBSIGMAR1ITGB3ITGAV | |
| SCHEMBL23868226 | 0.84 | ACACB (0.38) | ACACB | |
| SCHEMBL16000131 | 0.82 | ACACB (0.38) | ACACBSIGMAR1ITGB3ITGAV | |
| SCHEMBL23868150 | 0.78 | ACACB (0.35) | ACACB | |
| SCHEMBL25541391 | 0.72 | LMNA (0.33) | ITGB3ITGA2BANPEPERAP2ALOX15 | |
| SCHEMBL26694 | 0.71 | GABRA5 (0.39) | ANPEPERAP2ALOX15LMNACYP3A4 | |
| SCHEMBL8486385 | 0.71 | LMNA (0.45) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| Hydrochloric Acid SCHEMBL1902054 | 0.70 | GABRA5 (0.38) | ALOX15LMNACYP3A4GABRA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020073011-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. (US) | 2020-04-09 | — | — | WO | disclosed |