Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25541056 | 0.86 | ALDH1A1 (0.47) | TAAR1ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL16000106 | 0.82 | ACLY (0.46) | TAAR1ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL5460648 | 0.81 | TAAR1 (0.51) | TAAR1KMT2AMEN1BRD4PARP14 | |
| SCHEMBL4433007 | 0.81 | MEN1 (0.43) | ALDH1A1HTTKMT2AMEN1LMNA | |
| SCHEMBL4637575 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HTTKMT2AMEN1ADAMTS4 | |
| SCHEMBL16000102 | 0.81 | CNR1 (0.53) | TAAR1ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL18571230 | 0.80 | HTR2A (0.53) | TAAR1LMNAMAPTADAMTS4MMP13 | |
| SCHEMBL21885821 | 0.80 | BRD4 (0.47) | TAAR1KMT2ABRD4PARP14 | |
| SCHEMBL13234055 | 0.80 | KMT2A (0.49) | TAAR1ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL1998707 | 0.79 | ALDH1A1 (0.63) | ALDH1A1HTTKMT2AMEN1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020073011-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. (US) | 2020-04-09 | — | — | WO | disclosed |