Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LATS1 | O95835 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2447588 | 0.85 | L3MBTL1 (0.55) | L3MBTL1PTGDR2HTR6COMTKDM4E | |
| SCHEMBL14555161 | 0.82 | L3MBTL1 (0.53) | L3MBTL1PTGDR2HTR6COMTKDM4E | |
| SCHEMBL14816589 | 0.82 | L3MBTL1 (0.52) | L3MBTL1PTGDR2HTR6COMTKDM4E | |
| SCHEMBL20292949 | 0.82 | L3MBTL1 (0.52) | L3MBTL1PTGDR2HTR6COMTKDM4E | |
| SCHEMBL13858327 | 0.78 | TSHR (0.33) | L3MBTL1HTR6KDM4EUBE2NPKM | |
| SCHEMBL17394567 | 0.75 | HTR6 (0.58) | L3MBTL1PTGDR2HTR6SMN1; SMN2LMNA | |
| SCHEMBL1779514 | 0.75 | L3MBTL1 (0.60) | L3MBTL1PTGDR2HTR6COMTKDM4E | |
| SCHEMBL257136 | 0.74 | KDM4E (0.64) | L3MBTL1PTGDR2HTR6COMTKDM4E | |
| SCHEMBL13302164 | 0.74 | L3MBTL1 (0.59) | L3MBTL1PTGDR2HTR6COMTKDM4E | |
| SCHEMBL18634166 | 0.73 | L3MBTL1 (0.46) | L3MBTL1PTGDR2HTR6COMTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141548-B1 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES | VERTEX PHARMA (US) | 2020-04-08 | — | — | EP | disclosed |