Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 6/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20862126 | 0.88 | AOC3 (0.40) | ALDH1A1GAAKAT2BNOTUMNPC1 | |
| SCHEMBL21886536 | 0.87 | TNF (0.43) | TNFBRD4ALDH1A1GAAKAT2B | |
| SCHEMBL20862238 | 0.86 | TNF (0.37) | TNFBRD4ALDH1A1GAAKAT2B | |
| SCHEMBL24006724 | 0.83 | TNF (0.51) | TNFBRD4ALDH1A1GAAKAT2B | |
| SCHEMBL17598693 | 0.81 | BRD4 (0.41) | TNFBRD4ALDH1A1GAAKAT2B | |
| SCHEMBL21886547 | 0.80 | HSP90AA1 (0.32) | ALDH1A1GAANOTUM | |
| SCHEMBL22212862 | 0.80 | AOC3 (0.42) | KAT2BNOTUMNPC1POLBRAB9A | |
| SCHEMBL21886556 | 0.76 | AOC3 (0.40) | ALDH1A1GAAKAT2BNPC1RAB9A | |
| SCHEMBL16690286 | 0.75 | ALDH1A1 (0.37) | BRD4ALDH1A1GAANOTUMLMNA | |
| SCHEMBL20886088 | 0.74 | NPC1 (0.40) | ALDH1A1KAT2BNOTUMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063228-B1 | DISPERSE DYES, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DISTRIB GMBH (DE) | 2020-04-01 | — | — | EP | disclosed |