Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24006333 | 0.84 | KMT2A (0.33) | HSP90AA1KDM4EALDH1A1MAPTPKM | |
| SCHEMBL21886538 | 0.80 | TNF (0.39) | ALDH1A1GAANOTUM | |
| SCHEMBL20862126 | 0.79 | AOC3 (0.40) | KDM4EALDH1A1GAAMAPTNOTUM | |
| SCHEMBL8487393 | 0.75 | NOTUM (0.34) | ALDH1A1MAPTNOTUMPRMT5WDR77 | |
| SCHEMBL8312242 | 0.71 | RXRA (0.34) | HSP90AA1NOTUMPRMT5WDR77 | |
| SCHEMBL3009382 | 0.70 | CASP3 (0.41) | NOTUMATAD2 | |
| SCHEMBL28182834 | 0.70 | POLB (0.49) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL22212862 | 0.69 | AOC3 (0.42) | KDM4EMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL20862224 | 0.69 | MAPT (0.47) | HSP90AA1KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL29803467 | 0.67 | NOTUM (0.40) | NOTUMDRD2DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063228-B1 | DISPERSE DYES, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DISTRIB GMBH (DE) | 2020-04-01 | — | — | EP | disclosed |