Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17660490 | 0.84 | KMT2A (0.39) | APAF1KMT2AMEN1ANPEPKDM4E | |
| SCHEMBL17660491 | 0.78 | ROCK2 (0.38) | APAF1KMT2AMEN1KDM4EGRM7 | |
| SCHEMBL5376680 | 0.72 | ADRB3 (0.39) | KMT2AMEN1ADRA2AADRA1ACYP1A2 | |
| SCHEMBL925593 | 0.69 | ADRB2 (0.41) | KMT2AMEN1KDM4ECYP3A4ADRA2A | |
| SCHEMBL2831936 | 0.69 | ADRB2 (0.41) | KMT2AMEN1KDM4ECYP3A4ADRA2A | |
| SCHEMBL5028104 | 0.69 | UGT2B7 (0.35) | ALOX15ALOX12 | |
| SCHEMBL4801268 | 0.69 | ADRB3 (0.47) | KMT2AMEN1LMNA | |
| SCHEMBL5385110 | 0.68 | ROCK2 (0.38) | ALDH1A1 | |
| SCHEMBL5381523 | 0.68 | ROCK2 (0.38) | ALDH1A1 | |
| SCHEMBL828863 | 0.67 | ADRB2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3201171-B1 | METHOD OF PREPARING INTERMEDIATE OF SALMETEROL | AMPHASTAR NANJING PHARMACEUTICALS INC (CN) | 2020-04-15 | — | — | EP | disclosed |