Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22317927 | 0.89 | HRH3 (0.31) | HRH3CYP2D6 | |
| SCHEMBL15316686 | 0.88 | CYP2D6 (0.37) | HRH3CYP2D6 | |
| SCHEMBL15986914 | 0.85 | HRH3 (0.32) | HRH3 | |
| SCHEMBL13070658 | 0.83 | CYP2D6 (0.38) | HRH3CYP2D6 | |
| SCHEMBL10111446 | 0.83 | CYP2D6 (0.42) | HRH3CYP2D6 | |
| SCHEMBL24816716 | 0.82 | HRH3 (0.34) | HRH3CYP2D6 | |
| SCHEMBL12269696 | 0.82 | HRH3 (0.34) | HRH3CYP2D6 | |
| SCHEMBL22995782 | 0.82 | CYP2D6 (0.32) | HRH3CYP2D6 | |
| SCHEMBL10111441 | 0.80 | CYP2D6 (0.39) | HRH3CYP2D6 | |
| SCHEMBL19134103 | 0.80 | CYP2D6 (0.35) | HRH3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054604-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| US-11072585-B2 | Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof | PHARMAKEA, INC. (US) | 2021-07-27 | — | — | US | disclosed |
| US-20200115341-A1 | FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115341-A1 | FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | LOXL2, LOXL1, LOX | HRH3 2577/4885CYP2D6 1140/4885 |
| US-11072585-B2 | Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof | LOXL2, LOXL1, LOX | HRH3 2577/4885CYP2D6 1140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.