Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TK1 | P04183 | 3/20 | 0.36 |
| ▸ | TYMP | P19971 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12718326 | 0.88 | DHFR (0.41) | DHFRALDH1A1LMNAALBPOLB | |
| SCHEMBL21886783 | 0.88 | DHFR (0.41) | DHFRALDH1A1LMNAALBPOLB | |
| SCHEMBL21886784 | 0.88 | DHFR (0.41) | DHFRALDH1A1LMNAALBPOLB | |
| SCHEMBL25504743 | 0.88 | DHFR (0.41) | DHFRALDH1A1LMNAALBPOLB | |
| SCHEMBL2113192 | 0.88 | DHFR (0.41) | DHFRALDH1A1LMNAALBPOLB | |
| SCHEMBL22983990 | 0.86 | DHFR (0.37) | DHFRALDH1A1LMNAALBPOLB | |
| SCHEMBL25504742 | 0.86 | DHFR (0.37) | DHFRALDH1A1LMNAALBPOLB | |
| SCHEMBL31723487 | 0.83 | DHFR (0.36) | DHFRALDH1A1LMNAALBPOLB | |
| SCHEMBL25504789 | 0.82 | — | — | |
| SCHEMBL22984005 | 0.81 | DHFR (0.52) | DHFRLMNAALBBLMTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| WO-2020072991-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2020-04-09 | — | — | WO | disclosed |