Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | TK1 | P04183 | 5/20 | 0.47 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16964189 | 1.00 | DHFR (0.52) | DHFRTK1NT5MALBPKM | |
| SCHEMBL2431876 | 1.00 | DHFR (0.52) | DHFRTK1NT5MALBPKM | |
| SCHEMBL8514886 | 0.88 | TK1 (0.46) | DHFRTK1NT5MBLMPMP22 | |
| SCHEMBL12296875 | 0.83 | DHFR (0.39) | DHFRTK1 | |
| SCHEMBL16503451 | 0.83 | DUT (0.36) | DHFR | |
| SCHEMBL7859796 | 0.81 | TK1 (0.38) | DHFRTK1 | |
| SCHEMBL21886783 | 0.81 | DHFR (0.41) | DHFRTK1ALBLMNABLM | |
| SCHEMBL21886782 | 0.81 | DHFR (0.39) | DHFRTK1ALBLMNABLM | |
| SCHEMBL21886784 | 0.81 | DHFR (0.41) | DHFRTK1ALBLMNABLM | |
| SCHEMBL2113192 | 0.81 | DHFR (0.41) | DHFRTK1ALBLMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| EP-4013428-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | Ionis Pharmaceuticals, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |