Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570952 | 0.90 | KDM4C (0.50) | LMNAKDM4CPHF8KDM4AKDM2A | |
| SCHEMBL23191655 | 0.90 | ALDH1A1 (0.46) | LMNAKDM4CPHF8KDM4AKDM2A | |
| SCHEMBL11544855 | 0.84 | EPHX2 (0.57) | LMNAEPHX2MEN1FAAHKMT2A | |
| SCHEMBL11544852 | 0.84 | EPHX2 (0.57) | LMNAEPHX2MEN1FAAHKMT2A | |
| SCHEMBL5016930 | 0.83 | LMNA (0.58) | LMNAFFAR4FFAR1CES2CES1 | |
| SCHEMBL28987987 | 0.83 | LMNA (0.58) | LMNAFFAR4FFAR1CES2CES1 | |
| SCHEMBL12924011 | 0.83 | LMNA (0.58) | LMNAFFAR4FFAR1CES2CES1 | |
| SCHEMBL28723570 | 0.83 | LMNA (0.58) | LMNAKDM4CPHF8FFAR4FFAR1 | |
| SCHEMBL9657056 | 0.83 | LMNA (0.58) | LMNAKDM4CPHF8FFAR4FFAR1 | |
| SCHEMBL17501644 | 0.83 | LMNA (0.58) | LMNAKDM4CPHF8FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065408-A1 | SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | PIERRE FABRE MEDICAMENT (FR) | 2020-04-02 | — | — | WO | disclosed |