Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.62 |
| ▸ | MAOB | P27338 | 6/20 | 0.62 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31061343 | 0.89 | MAOA (0.71) | MAOAMAOBDDB1CRBNSLC6A2 | |
| SCHEMBL10795325 | 0.79 | HTR3A (0.55) | DDB1CRBNSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10798755 | 0.79 | CRBN (0.42) | MAOAMAOBDDB1CRBN | |
| SCHEMBL20002700 | 0.79 | DDB1 (0.42) | MAOAMAOBDDB1CRBNSLC6A2 | |
| SCHEMBL20002189 | 0.79 | DDB1 (0.42) | MAOAMAOBDDB1CRBNSLC6A2 | |
| SCHEMBL7899199 | 0.78 | SLC18A3 (0.41) | MAOAMAOBDDB1CRBN | |
| SCHEMBL23295265 | 0.78 | MAOA (0.96) | MAOAMAOBDDB1CRBNHRH3 | |
| Bromide SCHEMBL6874908 | 0.77 | NR1H2 (0.35) | MAOAMAOBSLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL6881930 | 0.77 | NR1H2 (0.35) | MAOAMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2578708 | 0.77 | MAOA (1.00) | MAOAMAOBDDB1CRBNHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020070610-A1 | NOVEL OXADIAZOLES | PI INDUSTRIES LTD. (IN) | 2020-04-09 | — | — | WO | disclosed |