SCHEMBL218876

SCHEMBL218876

O=C(O)C1=CC2CCC1C2

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.36
AKR1C3 P42330 1/20 0.33
AKR1C1 Q04828 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
MAPT P10636 1/20 0.32
OAT P04181 1/20 0.31
KMO O15229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5057907 1.00 CYP19A1 (0.36) CYP19A1AKR1C3AKR1C1HCAR2MAPT
SCHEMBL28451456 1.00 CYP19A1 (0.36) CYP19A1AKR1C3AKR1C1HCAR2MAPT
SCHEMBL5961832 0.92 MAPT (0.35) CYP19A1AKR1C3AKR1C1MAPT
Formic Acid SCHEMBL8030844 0.92 CYP19A1 (0.33) CYP19A1AKR1C3AKR1C1
SCHEMBL4315575 0.92 CYP19A1 (0.33) CYP19A1AKR1C3AKR1C1
SCHEMBL4297167 0.92 CYP19A1 (0.36) CYP19A1AKR1C3AKR1C1
SCHEMBL4701977 0.86 HCAR2 (0.34) AKR1C3AKR1C1HCAR2MAPTOAT
SCHEMBL2356043 0.86 SLC6A3 (0.38) CYP19A1
SCHEMBL9094883 0.86 CYP19A1 (0.33) CYP19A1
Maleic Anhydride SCHEMBL8030517 0.86 CYP19A1 (0.31) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12544455-B2 Targeted poly(beta-amino ester)s IXAKA FRANCE (FR) 2026-02-10 US claimed
US-20250345456-A1 Targeted Poly(beta-amino ester)s IXAKA FRANCE (FR) 2025-11-13 US claimed
US-20250259837-A1 RESPONSIVE LAYER FOR PHOTOLITHOGRAPHY FILM STACK APPLIED MATERIALS, INC. 2025-08-14 US claimed
US-20250161536-A1 CLICK-CROSSLINKED HYDROGELS AND METHODS OF USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2025-05-22 US claimed
EP-4547291-A1 LIGHT BEAM PROJECTION GUIDED BIOFABRICATION OF ALIGNED TISSUES ETH Zurich (CH) 2025-05-07 EP claimed
CN-119930418-A Preparation method of norbornene carboxylic acid 滨州魏桥国科高等技术研究院 2025-05-06 CN claimed
CN-119789880-A Biological manufacture of directional tissue guided by beam projection 苏黎世联邦理工学院 2025-04-08 CN claimed
CN-118684803-A Polydicyclopentadiene resin and preparation method thereof 四川大学 2024-09-24 CN claimed
CN-118613461-A Hybrid olefin composition comprising resin composition polymerizable by addition or polycondensation reaction 马特里亚公司 2024-09-06 CN claimed
US-12053561-B2 Click-crosslinked hydrogels and methods of use PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-08-06 US claimed
US-6358675-B1 PHOTORESISTS, PATTERNS, MULTISTAGE REACTION, COATING ON SUPPORTS A SILICON POLYMER, EXPOSURE TO ACTINIC RADIATION AND DEVELOPMENT OF LATENT IMAGES AND POLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2002-03-19 US claimed
EP-1078945-A2 Polymer for use in a photoresist composition SAMSUNG ELECTRONICS CO. LTD. (KR) 2001-02-28 EP claimed
US-6103445-A POLYMER OF A T-BUTYL ESTER OF NORBORNENE CARBOXYLIC ACID ANALOG, A PHOTOACID GENERATOR, AND PLASTICIZER COMPRISING A DI-TERT-BUTYL ESTER OF A POLYCYCLIC DICARBOXYLIC ACID; TRANSPARENCY AT 193 NM AND AN ETCH RESISTANCE; RESOLUTION BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2000-08-15 US claimed
US-6103450-A Photosensitive polymer, dissolution inhibitor and chemically amplified photoresist composition containing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-08-15 US claimed
US-6048664-A Energy-sensitive resist material and a process for device fabrication using an energy-sensitive resist material LUCENT TECHNOLOGIES, INC. (US) 2000-04-11 US claimed
US-5717098-A GAMMA-LACTONE CHEMICAL INTERMEDIATE, USED TO PRODUCE A SINGLE ENANTIOMER OF AMINOAZANORADAMANTANE WHICH IS COUPLED TO AROMATIC ACID DERIVEATIVE TO PRODUCE A COMPOUND USEFUL AS 5-HT-AGONISTS OR ANTAGONSITS G. D. SEARLE & CO. (US) 1998-02-10 US claimed
EP-0498618-B1 Stabilization of thiolene compositions LOCTITE CORP (US) 1995-04-26 EP claimed
WO-1993006171-A1 POLYMER BLENDS OF NORBORNENE DICARBOXIMIDES MONSANTO COMPANY (US) 1993-04-01 WO claimed
CN-1058014-A Polymerisable antioxidant and the olefin polymer that contains the antioxidant of binding STAMICARBON (NL) 1992-01-22 CN claimed
US-4987200-A METALLIZATION BEFORE POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 1991-01-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544455-B2 Targeted poly(beta-amino ester)s DNER, POTEE, BCAT1 CYP19A1 1830/4885AKR1C3 2353/4885AKR1C1 2298/4885
US-20250345456-A1 Targeted Poly(beta-amino ester)s POTEE, BCAT1, EBPL CYP19A1 4196/4885AKR1C3 4176/4885AKR1C1 3768/4885
US-20250161536-A1 CLICK-CROSSLINKED HYDROGELS AND METHODS OF USE VCL, CD44, LOX CYP19A1 4759/4885AKR1C3 4794/4885AKR1C1 4630/4885
US-12053561-B2 Click-crosslinked hydrogels and methods of use VCL, CD44, LOX CYP19A1 4759/4885AKR1C3 4794/4885AKR1C1 4630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.