Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | NMT1 | P30419 | 7/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21887706 | 0.84 | NR1H2 (0.61) | NR1H2SLC16A3SLC16A1CNR2NMT1 | |
| SCHEMBL16553781 | 0.80 | NR1H2 (0.74) | NR1H2SLC16A3SLC16A1 | |
| SCHEMBL16553610 | 0.77 | NR1H2 (0.42) | NR1H2SLC16A3SLC16A1 | |
| SCHEMBL21887746 | 0.76 | NR1H2 (0.45) | NR1H2SLC16A3SLC16A1TRPV1 | |
| SCHEMBL21887703 | 0.73 | NR1H2 (0.40) | NR1H2 | |
| SCHEMBL17970771 | 0.73 | NR1H2 (0.60) | NR1H2SLC16A3SLC16A1 | |
| SCHEMBL21887865 | 0.72 | NR1H2 (0.47) | NR1H2NMT1 | |
| SCHEMBL16553689 | 0.72 | NR1H2 (0.66) | NR1H2 | |
| SCHEMBL21887748 | 0.71 | NR1H2 (0.42) | NR1H2 | |
| SCHEMBL5014672 | 0.71 | SYK (0.39) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626712-A2 | LIVER X RECEPTOR (LXR) MODULATORS | Ellora Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |