Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.41 |
| ▸ | ATIC | P31939 | 2/20 | 0.34 |
| ▸ | FBP1 | P09467 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | EIF4E | P06730 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21888938 | 1.00 | PNP (0.41) | PNPATICFBP1LMNASMN1; SMN2 | |
| SCHEMBL21887954 | 0.90 | LMNA (0.42) | ATICFBP1LMNASMN1; SMN2ADORA1 | |
| SCHEMBL21887946 | 0.81 | LMNA (0.41) | ATICFBP1LMNASMN1; SMN2ADORA1 | |
| SCHEMBL21887982 | 0.81 | LMNA (0.41) | ATICFBP1LMNASMN1; SMN2ADORA1 | |
| SCHEMBL21888073 | 0.81 | PNP (0.48) | PNPATICFBP1LMNASMN1; SMN2 | |
| SCHEMBL21888254 | 0.81 | PNP (0.40) | PNPATICFBP1LMNASMN1; SMN2 | |
| SCHEMBL21887963 | 0.80 | LMNA (0.39) | ATICFBP1LMNASMN1; SMN2ADORA1 | |
| SCHEMBL21887944 | 0.80 | LMNA (0.39) | ATICFBP1LMNASMN1; SMN2ADORA1 | |
| SCHEMBL21887961 | 0.79 | LMNA (0.39) | ATICFBP1LMNASMN1; SMN2ADORA1 | |
| SCHEMBL21888087 | 0.77 | FBP1 (0.49) | ATICFBP1LMNASMN1; SMN2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072931-A2 | PRE-ACTIVATED NUCLEOSIDE IMPDH INHIBITORS AS ANTI-INFECTIVE DRUGS | OCTAGON THERAPEUTICS INC. (US) | 2020-04-09 | — | — | WO | disclosed |