Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | ATIC | P31939 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21888048 | 0.88 | LMNA (0.41) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL21888051 | 0.88 | LMNA (0.41) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL21888123 | 0.84 | LMNA (0.39) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL21888075 | 0.82 | LMNA (0.41) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL13082412 | 0.79 | LMNA (0.64) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL21888946 | 0.76 | LMNA (0.39) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL13082358 | 0.76 | P2RX3 (0.48) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL21888907 | 0.73 | LMNA (0.40) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL21887985 | 0.72 | LMNA (0.39) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL21888941 | 0.72 | LMNA (0.41) | LMNASMN1; SMN2ADORA1ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072931-A2 | PRE-ACTIVATED NUCLEOSIDE IMPDH INHIBITORS AS ANTI-INFECTIVE DRUGS | OCTAGON THERAPEUTICS INC. (US) | 2020-04-09 | — | — | WO | disclosed |