Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG7 | O95352 | 10/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21888108 | 0.81 | ATG7 (0.37) | ATG7LMNASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL9780396 | 0.81 | ATG7 (0.56) | ATG7LMNASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL21888937 | 0.80 | ATG7 (0.36) | ATG7LMNASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL21888891 | 0.74 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1GLAEIF4E | |
| SCHEMBL13754496 | 0.73 | LMNA (0.62) | LMNASMN1; SMN2ALDH1A1GLAEIF4E | |
| SCHEMBL13186258 | 0.73 | LMNA (0.62) | LMNASMN1; SMN2ALDH1A1GLAEIF4E | |
| SCHEMBL21888073 | 0.72 | PNP (0.48) | LMNASMN1; SMN2ALDH1A1GLAEIF4E | |
| SCHEMBL24024488 | 0.71 | LMNA (0.69) | ATG7LMNASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL21887965 | 0.71 | LMNA (0.42) | ATG7LMNASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL7572340 | 0.71 | LMNA (0.69) | ATG7LMNASMN1; SMN2ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072931-A2 | PRE-ACTIVATED NUCLEOSIDE IMPDH INHIBITORS AS ANTI-INFECTIVE DRUGS | OCTAGON THERAPEUTICS INC. (US) | 2020-04-09 | — | — | WO | disclosed |