SCHEMBL21888871

SCHEMBL21888871

C=CCOc1ccc(C2(c3ccc(OCC=C)c(N4C(=O)C=CC4=O)c3)c3ccccc3-c3ccccc32)cc1N1C(=O)C=CC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 1/20 0.35
▸ CA1 P00915 1/20 0.35
▸ CA9 Q16790 1/20 0.35
▸ MAPT P10636 2/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ OPRK1 P41145 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ PTPRC P08575 1/20 0.34
▸ MGLL Q99685 2/20 0.33
▸ GAA P10253 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ ESR1 P03372 1/20 0.33
▸ ESR2 Q92731 1/20 0.33
▸ TLR9 Q9NR96 1/20 0.33
▸ TXNRD1 Q16881 1/20 0.32
▸ TXNRD3 Q86VQ6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22550372 0.96 CA12 (0.33) CA12CA1CA9MAPTMEN1
SCHEMBL22892375 0.95 ALDH1A1 (0.33) CA12CA1CA9MAPTMEN1
SCHEMBL22550376 0.91 MGLL (0.35) CA12CA1CA9MAPTMEN1
SCHEMBL22550393 0.88 — —
SCHEMBL29849984 0.79 ESR1 (0.51) CA12CA1CA9MAPTMEN1
SCHEMBL22215860 0.79 ESR1 (0.51) CA12CA1CA9MAPTMEN1
SCHEMBL22550192 0.77 MAPT (0.47) CA12CA1CA9MAPTMEN1
SCHEMBL29850026 0.77 MAPT (0.47) CA12CA1CA9MAPTMEN1
SCHEMBL21888678 0.76 GAA (0.38) CA12CA1CA9MAPTKDM4E
SCHEMBL9321659 0.76 MGLL (0.56) CA12CA1CA9KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873356-B2 Curable composition and cured product thereof DIC CORPORATION (JP) 2024-01-16 — — US disclosed
US-11873356-B2 Curable composition and cured product thereof DIC CORPORATION (JP) 2024-01-16 — — US disclosed
US-10981865-B2 Substituted or unsubstituted allyl group-containing maleimide compound, production method therefor, and composition and cured product using said compound DIC CORPORATION (JP) 2021-04-20 — — US disclosed
US-20210032383-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF DIC CORPORATION (JP) 2021-02-04 — — US disclosed
US-20200325101-A1 SUBSTITUTED OR UNSUBSTITUTED ALLYL GROUP-CONTAINING MALEIMIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND COMPOSITION AND CURED PRODUCT USING SAID COMPOUND DIC CORPORATION (JP) 2020-10-15 — — US disclosed
US-20200109276-A1 COMPOSITION, CURED PRODUCT AND LAMINATE DIC CORPORATION (JP) 2020-04-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10981865-B2 Substituted or unsubstituted allyl group-containing maleimide compound, production method therefor, and composition and cured product using said compound BMI1, WEE1, WEE2 CA12 3973/4885CA1 4034/4885CA9 3007/4885
US-20200325101-A1 SUBSTITUTED OR UNSUBSTITUTED ALLYL GROUP-CONTAINING MALEIMIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND COMPOSITION AND CURED PRODUCT USING SAID COMPOUND BMI1, WEE1, WEE2 CA12 3973/4885CA1 4034/4885CA9 3007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback