SCHEMBL21889685

SCHEMBL21889685

Cc1cccc(C2C(=O)Oc3c(C)cccc32)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 5/20 0.41
HTR2A P28223 3/20 0.41
HTR2B P41595 3/20 0.41
PBRM1 Q86U86 1/20 0.35
HPGD P15428 1/20 0.35
GAA P10253 1/20 0.33
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
MAPT P10636 3/20 0.32
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
THRB P10828 1/20 0.32
KMT2A Q03164 1/20 0.32
TP53 P04637 1/20 0.32
HTT P42858 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
CD44 P16070 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25723546 0.88 HPGD (0.41) HTR2CHTR2AHTR2BPBRM1HPGD
SCHEMBL25723566 0.86 GAA (0.38) HTR2CHTR2AHTR2BPBRM1HPGD
SCHEMBL25723550 0.82 GAA (0.43) PBRM1HPGDGAAMAPTMEN1
SCHEMBL25724165 0.81 GAA (0.45) HTR2CHTR2AHTR2BHPGDGAA
SCHEMBL2614948 0.81 GAA (0.53) HTR2BHPGDGAAMAPTMEN1
SCHEMBL25723558 0.81 HTT (0.36) HTR2CHTR2AHTR2BHPGDGAA
SCHEMBL25723552 0.81 ALDH1A1 (0.43) HPGDMAPTMEN1KMT2ATP53
SCHEMBL21889683 0.80 GAA (0.48) HPGDGAAMAPTMEN1THRB
SCHEMBL25723549 0.78 GAA (0.39) HTR2CHTR2AHTR2BHPGDGAA
SCHEMBL25723561 0.78 GAA (0.49) HTR2CHTR2AHTR2BPBRM1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203353-A1 ADHESIVE FOR ENDOSCOPE AND CURED PRODUCT THEREOF, AND ENDOSCOPE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2023-06-29 US disclosed
US-20230203353-A1 ADHESIVE FOR ENDOSCOPE AND CURED PRODUCT THEREOF, AND ENDOSCOPE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2023-06-29 US disclosed
US-20230157720-A1 ENDOSCOPIC FLEXIBLE TUBE, ENDOSCOPIC MEDICAL APPARATUS, AND ENDOSCOPIC-FLEXIBLE-TUBE-BASE-COVERING MATERIAL FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-20230157720-A1 ENDOSCOPIC FLEXIBLE TUBE, ENDOSCOPIC MEDICAL APPARATUS, AND ENDOSCOPIC-FLEXIBLE-TUBE-BASE-COVERING MATERIAL FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-11540702-B2 Flexible tube for endoscope, endoscopic medical device, resin composition for covering flexible tube substrate for endoscope, and set of resin compositions for covering flexible tube substrate for endoscope FUJIFILM CORPORATION (JP) 2023-01-03 US disclosed
US-20200107697-A1 FLEXIBLE TUBE FOR ENDOSCOPE, ENDOSCOPIC MEDICAL DEVICE, RESIN COMPOSITION FOR COVERING FLEXIBLE TUBE SUBSTRATE FOR ENDOSCOPE, AND SET OF RESIN COMPOSITIONS FOR COVERING FLEXIBLE TUBE SUBSTRATE FOR ENDOSCOPE FUJIFILM CORPORATION (JP) 2020-04-09 US disclosed