SCHEMBL2614948

SCHEMBL2614948

Cc1cccc2c1OC(=O)C2c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.53
ALDH1A1 P00352 4/20 0.40
MAPT P10636 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
ALOX15 P16050 1/20 0.40
CASP1 P29466 1/20 0.40
RECQL P46063 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GFER P55789 1/20 0.37
CYP3A4 P08684 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HPGD P15428 1/20 0.37
ALDH2 P05091 1/20 0.36
TP53 P04637 2/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21889683 0.89 GAA (0.48) GAAALDH1A1MAPTMEN1KMT2A
SCHEMBL25723546 0.86 HPGD (0.41) GAAALDH1A1MAPTMEN1KMT2A
SCHEMBL21889686 0.86 GAA (0.41) GAAALDH1A1MAPTMEN1KMT2A
SCHEMBL25723561 0.86 GAA (0.49) GAAALDH1A1MAPTMEN1KMT2A
SCHEMBL25723549 0.83 GAA (0.39) GAAMAPTMEN1KMT2AHPGD
SCHEMBL21889685 0.81 HTR2C (0.41) GAAMAPTMEN1KMT2AHPGD
SCHEMBL12352206 0.81 GAA (0.61) GAAALDH1A1MAPTMEN1KMT2A
SCHEMBL25723552 0.80 ALDH1A1 (0.43) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL25723558 0.80 HTT (0.36) GAAMAPTMEN1KMT2AHPGD
SCHEMBL11210296 0.78 GAA (0.51) GAAALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203353-A1 ADHESIVE FOR ENDOSCOPE AND CURED PRODUCT THEREOF, AND ENDOSCOPE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2023-06-29 US disclosed
US-20230203353-A1 ADHESIVE FOR ENDOSCOPE AND CURED PRODUCT THEREOF, AND ENDOSCOPE AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2023-06-29 US disclosed
US-20230157720-A1 ENDOSCOPIC FLEXIBLE TUBE, ENDOSCOPIC MEDICAL APPARATUS, AND ENDOSCOPIC-FLEXIBLE-TUBE-BASE-COVERING MATERIAL FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-11540702-B2 Flexible tube for endoscope, endoscopic medical device, resin composition for covering flexible tube substrate for endoscope, and set of resin compositions for covering flexible tube substrate for endoscope FUJIFILM CORPORATION (JP) 2023-01-03 US disclosed
US-20200107697-A1 FLEXIBLE TUBE FOR ENDOSCOPE, ENDOSCOPIC MEDICAL DEVICE, RESIN COMPOSITION FOR COVERING FLEXIBLE TUBE SUBSTRATE FOR ENDOSCOPE, AND SET OF RESIN COMPOSITIONS FOR COVERING FLEXIBLE TUBE SUBSTRATE FOR ENDOSCOPE FUJIFILM CORPORATION (JP) 2020-04-09 US disclosed
US-20130306151-A1 ORGANIC PHOTOVOLTAIC DEVICE AND MANUFACTURING METHOD THEREOF BASF SE (DE) 2013-11-21 US disclosed
US-20120328541-A1 Anti-radical agents BASCHONG WERNER (CH) 2012-12-27 US disclosed
US-20120093896-A1 USE OF NANODISPERSIONS TO PROTECT WATER-SOLUBLE INGREDIENTS IN COSMETIC END FORMULATIONS CIBA CORPORATION (US) 2012-04-19 US disclosed
US-20090258041-A1 Protection of Oxidizable Agents CIBA CORP. 2009-10-15 US disclosed
US-20080305055-A1 Anti-Radical Agents CIBA CORPORATION 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120328541-A1 Anti-radical agents NOS3, GSTO1, TXN2 GAA 4827/4885ALDH1A1 881/4885MAPT 4702/4885
US-20080305055-A1 Anti-Radical Agents NOS3, GSTO1, PTGS1 GAA 4532/4885ALDH1A1 806/4885MAPT 4783/4885
US-20090258041-A1 Protection of Oxidizable Agents LPO, TYR, HAO2 GAA 295/4885ALDH1A1 379/4885MAPT 2327/4885
US-20120093896-A1 USE OF NANODISPERSIONS TO PROTECT WATER-SOLUBLE INGREDIENTS IN COSMETIC END FORMULATIONS CUTA, PROC, RBP1 GAA 1892/4885ALDH1A1 316/4885MAPT 3394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.