Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RARB | P10826 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21889396 | 0.95 | HTT (0.62) | HTTPOLBAPEX1TDP1ELANE | |
| SCHEMBL21889394 | 0.91 | POLB (0.58) | HTTPOLBAPEX1TDP1ELANE | |
| SCHEMBL15084291 | 0.91 | HTT (0.81) | HTTPOLBAPEX1TDP1ELANE | |
| SCHEMBL14400544 | 0.90 | HTT (0.73) | HTTPOLBAPEX1TDP1L3MBTL1 | |
| SCHEMBL13289974 | 0.88 | HTT (0.76) | HTTPOLBAPEX1TDP1L3MBTL1 | |
| SCHEMBL16982216 | 0.88 | HTT (0.76) | HTTPOLBAPEX1TDP1L3MBTL1 | |
| SCHEMBL13220831 | 0.88 | HTT (0.76) | HTTPOLBAPEX1TDP1L3MBTL1 | |
| SCHEMBL10050687 | 0.88 | HTT (0.60) | HTTPOLBAPEX1TDP1ELANE | |
| SCHEMBL21888879 | 0.88 | HTT (0.57) | HTTPOLBAPEX1TDP1ELANE | |
| SCHEMBL21888880 | 0.87 | TDP1 (0.56) | HTTPOLBAPEX1TDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954183-B2 | Curable composition, semi-cured product, cured product, optical member, lens, and compound | FUJIFILM CORPORATION (JP) | 2021-03-23 | — | — | US | disclosed |
| US-20200115316-A1 | CURABLE COMPOSITION, SEMI-CURED PRODUCT, CURED PRODUCT, OPTICAL MEMBER, LENS, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115316-A1 | CURABLE COMPOSITION, SEMI-CURED PRODUCT, CURED PRODUCT, OPTICAL MEMBER, LENS, AND COMPOUND | CRYAA, Q6ZSR9, CRYZ | HTT 698/4885POLB 3686/4885APEX1 4544/4885 |
| US-10954183-B2 | Curable composition, semi-cured product, cured product, optical member, lens, and compound | CRYAA, Q6ZSR9, CRYZ | HTT 698/4885POLB 3686/4885APEX1 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.