Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186765 | 0.82 | KMT2A (0.43) | KMT2AMEN1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL6306700 | 0.81 | KMT2A (0.45) | KMT2AMEN1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL22408214 | 0.77 | KMT2A (0.66) | KMT2AMEN1CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL10587921 | 0.75 | KMT2A (0.37) | KMT2AMEN1CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL2188574 | 0.75 | INPPL1 (0.45) | KMT2AMEN1CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL2185749 | 0.73 | ALDH1A1 (0.60) | KMT2AMEN1CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL2187940 | 0.73 | KMT2A (0.45) | KMT2AMEN1CYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL9025506 | 0.73 | KMT2A (0.36) | KMT2AMEN1CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL2187113 | 0.72 | ALDH1A1 (0.54) | KMT2AMEN1RXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2188417 | 0.71 | ALDH1A1 (0.43) | KMT2AMEN1CYP1A2RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | claimed |