Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22408141 | 0.79 | KMT2A (0.65) | INPPL1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL2185749 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1GAACYP1A2 | |
| SCHEMBL2187940 | 0.79 | KMT2A (0.45) | ALDH1A1KMT2AMEN1GAACYP1A2 | |
| SCHEMBL2188510 | 0.77 | KDM4E (0.61) | INPPL1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL2186717 | 0.76 | MAPT (0.52) | ALDH1A1KMT2AMEN1GAACYP1A2 | |
| SCHEMBL13753386 | 0.76 | SMN1; SMN2 (0.55) | ALDH1A1GAASMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL2185826 | 0.75 | ALOX5 (0.41) | ALDH1A1KMT2AMEN1GAAHSD17B10 | |
| SCHEMBL2188506 | 0.75 | L3MBTL1 (0.45) | ALDH1A1KMT2AMEN1GAACYP1A2 | |
| SCHEMBL13753378 | 0.75 | POLB (0.46) | INPPL1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL2188985 | 0.75 | KMT2A (0.39) | ALDH1A1KMT2AMEN1CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | claimed |