SCHEMBL21890267

SCHEMBL21890267

c1ccc(-n2c3ccccc3c3cc4c(cc32)c2ccc(-c3nc5ccccc5[nH]3)cc2n4-c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 10/20 0.49
▸ RAB9A P51151 10/20 0.49
▸ GAA P10253 1/20 0.49
▸ SMN1; SMN2 Q16637 11/20 0.46
▸ POLB P06746 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ NPY5R Q15761 1/20 0.46
▸ KDM4E B2RXH2 11/20 0.45
▸ ALDH1A1 P00352 10/20 0.45
▸ HPGD P15428 8/20 0.45
▸ MAPT P10636 5/20 0.45
▸ PKM P14618 3/20 0.45
▸ LMNA P02545 2/20 0.45
▸ NFKB1 P19838 1/20 0.45
▸ NFKB2 Q00653 1/20 0.45
▸ RELA Q04206 1/20 0.45
▸ HSD17B10 Q99714 5/20 0.45
▸ TP53 P04637 3/20 0.45
▸ HDAC6 Q9UBN7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21298160 0.97 NPC1 (0.51) NPC1RAB9AGAASMN1; SMN2POLB
SCHEMBL21890438 0.96 NPC1 (0.48) NPC1RAB9AGAASMN1; SMN2POLB
SCHEMBL21298554 0.93 NPY5R (0.53) NPC1RAB9AGAASMN1; SMN2POLB
SCHEMBL23948708 0.92 NPY5R (0.50) NPC1RAB9AGAASMN1; SMN2POLB
SCHEMBL21890463 0.91 NPC1 (0.47) NPC1RAB9AGAASMN1; SMN2POLB
SCHEMBL24501022 0.88 NPC1 (0.50) NPC1RAB9AGAASMN1; SMN2POLB
SCHEMBL21890530 0.88 NPC1 (0.42) NPC1RAB9AGAASMN1; SMN2POLB
SCHEMBL21890257 0.88 NPC1 (0.42) NPC1RAB9AGAASMN1; SMN2POLB
SCHEMBL21890491 0.87 NPC1 (0.41) NPC1RAB9AGAASMN1; SMN2POLB
SCHEMBL21890264 0.85 NPC1 (0.41) NPC1RAB9AGAASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2023-03-02 — — US disclosed
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-07-16 — — US disclosed
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ NPC1 2679/4885RAB9A 1671/4885GAA 3249/4885
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ NPC1 2679/4885RAB9A 1671/4885GAA 3249/4885
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues SUN2, STAU1, HELZ NPC1 2679/4885RAB9A 1671/4885GAA 3249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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