Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.42 |
| ▸ | RAB9A | P51151 | 9/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21890257 | 1.00 | NPC1 (0.42) | NPC1RAB9AGAANPY5RSMN1; SMN2 | |
| SCHEMBL23948926 | 0.95 | NPY5R (0.44) | NPC1RAB9AGAANPY5RSMN1; SMN2 | |
| SCHEMBL21890463 | 0.92 | NPC1 (0.47) | NPC1RAB9AGAANPY5RSMN1; SMN2 | |
| SCHEMBL21298160 | 0.90 | NPC1 (0.51) | NPC1RAB9AGAANPY5RSMN1; SMN2 | |
| SCHEMBL21890267 | 0.88 | NPC1 (0.49) | NPC1RAB9AGAANPY5RSMN1; SMN2 | |
| SCHEMBL21890438 | 0.87 | NPC1 (0.48) | NPC1RAB9AGAANPY5RSMN1; SMN2 | |
| SCHEMBL21298554 | 0.85 | NPY5R (0.53) | NPC1RAB9AGAANPY5RSMN1; SMN2 | |
| SCHEMBL23948708 | 0.85 | NPY5R (0.50) | NPC1RAB9AGAANPY5RSMN1; SMN2 | |
| SCHEMBL21890263 | 0.84 | CHEK2 (0.44) | NPC1RAB9AGAASMN1; SMN2POLB | |
| SCHEMBL21890260 | 0.83 | SMN1; SMN2 (0.40) | NPC1RAB9AGAASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230068759-A1 | DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2023-03-02 | — | — | US | disclosed |
| US-20200227656-A1 | DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2020-07-16 | — | — | US | disclosed |
| US-10615349-B2 | Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200227656-A1 | DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES | SUN2, STAU1, HELZ | NPC1 2679/4885RAB9A 1671/4885GAA 3249/4885 |
| US-20230068759-A1 | DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES | SUN2, STAU1, HELZ | NPC1 2679/4885RAB9A 1671/4885GAA 3249/4885 |
| US-10615349-B2 | Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues | SUN2, STAU1, HELZ | NPC1 2679/4885RAB9A 1671/4885GAA 3249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.