SCHEMBL21890441

SCHEMBL21890441

c1ccc(-n2c3ccccc3c3ccc4c5ccccc5c5nc6ccccc6n5c4c32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.50
MAPT P10636 5/20 0.50
LMNA P02545 3/20 0.50
POLB P06746 2/20 0.50
HSD17B10 Q99714 2/20 0.50
TP53 P04637 2/20 0.50
ALDH1A1 P00352 7/20 0.49
HPGD P15428 6/20 0.49
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
KMT2A Q03164 4/20 0.47
MEN1 O00255 2/20 0.47
SMN1; SMN2 Q16637 3/20 0.44
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
CAMKK1 Q8N5S9 2/20 0.41
CAMKK2 Q96RR4 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22649056 0.94 KDM4E (0.53) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL16066195 0.91 KDM4E (0.43) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL24290720 0.89 KDM4E (0.43) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL16066348 0.89 KDM4E (0.48) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL24290635 0.89 KDM4E (0.43) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL10041551 0.88 KDM4E (0.45) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL16066132 0.88 HPGD (0.53) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL16066344 0.88 KDM4E (0.47) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL22649299 0.87 KDM4E (0.44) KDM4EMAPTLMNAPOLBHSD17B10
SCHEMBL16066361 0.87 KDM4E (0.49) KDM4EMAPTLMNAPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2023-03-02 US disclosed
US-20220073517-A1 BLUE THERMALLY ACTIVATED DELAYED FLUORESCENT EMITTERS AND HOSTS BASED ON FUNCTIONALIZED IMIDAZOLYL GROUPS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2022-03-10 US disclosed
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-07-16 US disclosed
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220073517-A1 BLUE THERMALLY ACTIVATED DELAYED FLUORESCENT EMITTERS AND HOSTS BASED ON FUNCTIONALIZED IMIDAZOLYL GROUPS IK, ETFA, GDI1 KDM4E 3679/4885MAPT 690/4885LMNA 2844/4885
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ KDM4E 4206/4885MAPT 2512/4885LMNA 2450/4885
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ KDM4E 4206/4885MAPT 2512/4885LMNA 2450/4885
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues SUN2, STAU1, HELZ KDM4E 4206/4885MAPT 2512/4885LMNA 2450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.