SCHEMBL21890446

SCHEMBL21890446

c1ccc(-n2c3cc(-c4ncc[nH]4)ccc3c3c2ccc2c4ccccc4n(-c4ccccc4)c23)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ NISCH Q9Y2I1 2/20 0.40
▸ MTOR P42345 1/20 0.40
▸ ADK P55263 1/20 0.40
▸ KDM4E B2RXH2 2/20 0.39
▸ ATM Q13315 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ MAPK8 P45983 2/20 0.37
▸ JAK2 O60674 1/20 0.36
▸ JAK3 P52333 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.33
▸ VCP P55072 4/20 0.31
▸ TLR9 Q9NR96 1/20 0.31
▸ TLR8 Q9NR97 1/20 0.31
▸ TLR7 Q9NYK1 1/20 0.31
▸ MAP3K14 Q99558 1/20 0.31
▸ NPY5R Q15761 1/20 0.30
▸ AKT1 P31749 1/20 0.30
▸ AKT2 P31751 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21890402 1.00 NISCH (0.40) NISCHMTORADKKDM4EATM
SCHEMBL21890527 0.92 NISCH (0.44) NISCHMTORADKKDM4EATM
SCHEMBL19501106 0.83 L3MBTL1 (0.53) KDM4EATML3MBTL1MAPK8JAK2
SCHEMBL19501114 0.83 L3MBTL1 (0.53) KDM4EATML3MBTL1MAPK8JAK2
SCHEMBL24291200 0.83 TRPV1 (0.35) NISCHMTORADKKDM4EATM
SCHEMBL21890256 0.82 NISCH (0.37) NISCHMTORADKKDM4EMAPK8
SCHEMBL16641296 0.81 L3MBTL1 (0.50) KDM4EATML3MBTL1MAPK8JAK2
SCHEMBL23008163 0.81 L3MBTL1 (0.50) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL23008170 0.81 L3MBTL1 (0.50) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL19769651 0.81 L3MBTL1 (0.50) KDM4EATML3MBTL1JAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2023-03-02 — — US disclosed
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-07-16 — — US disclosed
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ NISCH 10/4885MTOR 3918/4885ADK 1495/4885
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ NISCH 10/4885MTOR 3918/4885ADK 1495/4885
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues SUN2, STAU1, HELZ NISCH 10/4885MTOR 3918/4885ADK 1495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback