SCHEMBL21890465

SCHEMBL21890465

c1ccc(-n2c3ccccc3c3cc4c(cc32)c2cccnc2c2cc3c(cc42)c2ccccc2n3-c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
ATM Q13315 1/20 0.53
FEN1 P39748 1/20 0.37
PDE4A P27815 6/20 0.36
PDE4B Q07343 5/20 0.36
PDE4C Q08493 5/20 0.36
PDE4D Q08499 5/20 0.36
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
LOXL3 P58215 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
CYP2C19 P33261 1/20 0.36
KAT2B Q92831 1/20 0.33
LDHA P00338 1/20 0.33
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21890472 1.00 KDM4E (0.53) KDM4EL3MBTL1ATMFEN1PDE4A
SCHEMBL21890452 0.99 KDM4E (0.51) KDM4EL3MBTL1ATMFEN1PDE4A
SCHEMBL21890849 0.99 KDM4E (0.51) KDM4EL3MBTL1ATMFEN1PDE4A
SCHEMBL21890352 0.97 KDM4E (0.53) KDM4EL3MBTL1ATMFEN1PDE4A
SCHEMBL21890208 0.97 KDM4E (0.53) KDM4EL3MBTL1ATMFEN1PDE4A
SCHEMBL21890850 0.95 L3MBTL1 (0.55) KDM4EL3MBTL1ATMFEN1PDE4A
SCHEMBL21890846 0.91 L3MBTL1 (0.53) KDM4EL3MBTL1ATMFEN1PDE4A
SCHEMBL19651078 0.91 L3MBTL1 (0.53) KDM4EL3MBTL1ATMFEN1PDE4A
SCHEMBL21890473 0.91 L3MBTL1 (0.56) KDM4EL3MBTL1ATMFEN1PDE4A
SCHEMBL19651098 0.91 L3MBTL1 (0.56) KDM4EL3MBTL1ATMFEN1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2023-03-02 US disclosed
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-07-16 US disclosed
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ KDM4E 4206/4885L3MBTL1 1232/4885ATM 3709/4885
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ KDM4E 4206/4885L3MBTL1 1232/4885ATM 3709/4885
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues SUN2, STAU1, HELZ KDM4E 4206/4885L3MBTL1 1232/4885ATM 3709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.