SCHEMBL21890479

SCHEMBL21890479

c1ccc(-n2c3cc(-c4ncc[nH]4)ccc3c3c4c(ccc32)oc2ccccc24)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NISCH Q9Y2I1 2/20 0.38
▸ MTOR P42345 1/20 0.38
▸ ADK P55263 1/20 0.38
▸ ADRA2A P08913 2/20 0.37
▸ MAPK8 P45983 1/20 0.36
▸ F2RL1 P55085 2/20 0.34
▸ JAK2 O60674 1/20 0.33
▸ JAK3 P52333 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ CA12 O43570 1/20 0.31
▸ CA9 Q16790 1/20 0.31
▸ CHEK2 O96017 1/20 0.31
▸ SMN1; SMN2 Q16637 2/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ CASP3 P42574 1/20 0.31
▸ SENP7 Q9BQF6 1/20 0.31
▸ SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21890527 0.88 NISCH (0.44) NISCHMTORADKMAPK8JAK2
SCHEMBL21890532 0.82 CHEK2 (0.44) KDM4EALDH1A1CHEK2SMN1; SMN2LMNA
SCHEMBL19830381 0.81 KDM4E (0.39) JAK2JAK3KDM4EALDH1A1CA12
SCHEMBL21890446 0.81 NISCH (0.40) NISCHMTORADKMAPK8JAK2
SCHEMBL21890402 0.81 NISCH (0.40) NISCHMTORADKMAPK8JAK2
SCHEMBL21890467 0.80 NISCH (0.37) NISCHMTORADKMAPK8JAK2
SCHEMBL19830376 0.80 KDM4E (0.41) JAK2JAK3KDM4EALDH1A1SMN1; SMN2
SCHEMBL19830773 0.80 KDM4E (0.41) JAK2JAK3KDM4EALDH1A1SMN1; SMN2
SCHEMBL21890443 0.78 NISCH (0.37) NISCHMTORADKMAPK8JAK2
SCHEMBL24676610 0.77 ATM (0.41) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2023-03-02 — — US disclosed
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2020-07-16 — — US disclosed
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200227656-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ NISCH 10/4885MTOR 3918/4885ADK 1495/4885
US-20230068759-A1 DONOR-ACCEPTOR TYPE THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIALS BASED ON IMIDAZO[1,2-F]PHENANTHRIDINE AND ANALOGUES SUN2, STAU1, HELZ NISCH 10/4885MTOR 3918/4885ADK 1495/4885
US-10615349-B2 Donor-acceptor type thermally activated delayed fluorescent materials based on imidazo[1,2-F]phenanthridine and analogues SUN2, STAU1, HELZ NISCH 10/4885MTOR 3918/4885ADK 1495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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