SCHEMBL2189067

SCHEMBL2189067

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nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 2/20 0.33
TRPV1 Q8NER1 1/20 0.33
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1578687 0.89 LMNA (0.34) TDP1TSHRTRPV1
SCHEMBL1578684 0.89 LMNA (0.34) TDP1TSHRTRPV1
SCHEMBL10509214 0.84 TDP1 (0.38) TDP1TSHRTRPV1CHRM2CHRM4
SCHEMBL13687836 0.81 TDP1 (0.42) TDP1TSHRTRPV1CHRM2CHRM4
SCHEMBL11472471 0.81 TDP1 (0.42) TDP1TSHRTRPV1CHRM2CHRM4
SCHEMBL10507699 0.79 TDP1 (0.43) TDP1TSHRTRPV1
SCHEMBL10507704 0.79 TDP1 (0.43) TDP1TSHRTRPV1
SCHEMBL10506282 0.79 TDP1 (0.43) TDP1TSHRTRPV1
SCHEMBL10511575 0.79 TDP1 (0.43) TDP1TSHRTRPV1
SCHEMBL10506288 0.79 TDP1 (0.43) TDP1TSHRTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2341772-A1 SYNTHESIS OF DECITABINE ScinoPharm Taiwan, Ltd. (TW) 2011-07-13 EP claimed
WO-2010040056-A1 SYNTHESIS OF DECITABINE SCINOPHARM TAIWAN LTD. (TW) 2010-04-08 WO claimed
EP-2341772-A1 SYNTHESIS OF DECITABINE ScinoPharm Taiwan, Ltd. (TW) 2011-07-13 EP disclosed
WO-2010040056-A1 SYNTHESIS OF DECITABINE SCINOPHARM TAIWAN LTD. (TW) 2010-04-08 WO disclosed