Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455667 | 0.79 | — | — | |
| SCHEMBL3225026 | 0.76 | — | — | |
| SCHEMBL3215300 | 0.74 | — | — | |
| SCHEMBL1419567 | 0.74 | — | — | |
| SCHEMBL3219040 | 0.74 | — | — | |
| SCHEMBL455469 | 0.74 | — | — | |
| SCHEMBL5967417 | 0.70 | ALDH1A1 (0.36) | HDAC8 | |
| SCHEMBL7595227 | 0.70 | HDAC8 (0.30) | HDAC8 | |
| SCHEMBL15988598 | 0.70 | CES2 (0.33) | — | |
| SCHEMBL456783 | 0.70 | CYP1A1 (0.31) | HDAC8CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195492-B | Novel compound with three-fused ring structure, preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-113195492-A | Novel compound with three-fused ring structure, preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-112538084-A | Novel KRAS G12C protein inhibitor and preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-112430234-A | Novel KRAS G12C protein inhibitor and preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-112292374-A | Novel phosphoinositide 3-kinase inhibitor and preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2021-01-29 | — | — | CN | disclosed |
| CN-110684048-A | Novel phosphoinositide 3-kinase inhibitor and preparation method and application thereof | 信达生物制药(苏州)有限公司 | 2020-01-14 | — | — | CN | disclosed |
| US-8524847-B2 | Organic insulating material, varnish for resin film using the same, resin film and semiconductor device | SUMITOMO BAKELITE CO., LTD. (JP) | 2013-09-03 | — | — | US | disclosed |
| EP-2157107-B1 | ORGANIC INSULATING MATERIAL, VARNISH FOR RESIN FILM USING THE SAME, RESIN FILM AND SEMICONDUCTOR DEVICE | SUMITOMO BAKELITE CO (JP) | 2013-05-08 | — | — | EP | disclosed |
| CN-101646697-B | Organic insulating material, varnish for resin film using the same, resin film, and semiconductor device | SUMITOMO BAKELITE CO JP | 2012-07-04 | — | — | CN | disclosed |
| US-20110172351-A1 | ORGANIC INSULATING MATERIAL, VARNISH FOR RESIN FILM USING THE SAME, RESIN FILM AND SEMICONDUCTOR DEVICE | SUMITOMO BAKELITE CO., LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
| CN-101689411-A | Organic insulating material, varnish for organic insulating film using the same, organic insulating film, and semiconductor device | SUMITOMO BAKELITE CO | 2010-03-31 | — | — | CN | disclosed |
| EP-2157107-A1 | ORGANIC INSULATING MATERIAL, VARNISH FOR RESIN FILM USING THE SAME, RESIN FILM AND SEMICONDUCTOR DEVICE | Sumitomo Bakelite Co., Ltd. (JP) | 2010-02-24 | — | — | EP | disclosed |
| CN-101646697-A | Organic insulating material, varnish for resin film using the same, resin film, and semiconductor device | SUMITOMO BAKELITE CO JP | 2010-02-10 | — | — | CN | disclosed |
| US-20100004379-A1 | ORGANIC INSULATING MATERIAL, VARNISH FOR RESIN FILM USING THE SAME, RESIN FILM AND SEMICONDUCTOR DEVICE | SUMITOMO BAKELITE CO., LTD. (JP) | 2010-01-07 | — | — | US | disclosed |
| US-20090318610-A1 | ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES | SUMITOMO BAKELITE CO., LTD (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2117009-A1 | ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE | Sumitomo Bakelite Co., Ltd. (JP) | 2009-11-11 | — | — | EP | disclosed |