SCHEMBL218916

SCHEMBL218916

CC(=O)CC(=O)OCC(COC(=O)CC(C)=O)(COC(=O)CC(C)=O)COC(=O)CC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.52
GAA P10253 2/20 0.52
SI P14410 2/20 0.52
MGAM2 Q2M2H8 2/20 0.52
MAPK1 P28482 2/20 0.34
HIF1A Q16665 2/20 0.34
HTT P42858 1/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 5/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.31
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL649062 0.93 MGAM (0.46) MGAMGAASIMGAM2MAPK1
SCHEMBL16411252 0.89 MGAM (0.46) MGAMGAASIMGAM2MAPK1
SCHEMBL9571839 0.89 MGAM (0.46) MGAMGAASIMGAM2MAPK1
SCHEMBL651229 0.89 MGAM (0.46) MGAMGAASIMGAM2MAPK1
SCHEMBL22050939 0.89 MGAM (0.46) MGAMGAASIMGAM2ALDH1A1
SCHEMBL649818 0.89 MGAM (0.46) MGAMGAASIMGAM2MAPK1
SCHEMBL2703174 0.86 MGAM (0.40) MGAMGAASIMGAM2MAPK1
SCHEMBL22124844 0.83 THRB (0.42) MGAMGAASIMGAM2
SCHEMBL8999875 0.83 MGAM (0.41) MGAMGAASIMGAM2MAPK1
SCHEMBL17746191 0.83 MGAM (0.41) MGAMGAASIMGAM2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114302928-B Coating compositions curable by acetylmichael addition 巴斯夫涂料有限公司 2024-04-16 CN claimed
CN-110691798-B Low temperature curable composition 伊士曼化工公司 2023-09-08 CN claimed
US-11732165-B2 Low-temperature curable compositions EASTMAN CHEMICAL COMPANY (US) 2023-08-22 US claimed
WO-2023139231-A1 RESIN COMPOSITION ARXADA AG (CH) 2023-07-27 WO claimed
US-20220290002-A1 COATING COMPOSITION CURABLE BY ACETO-MICHAEL ADDITION BASF COATINGS GMBH (DE) 2022-09-15 US claimed
EP-3662044-B1 DETERGENT ADDITIVE DOW GLOBAL TECHNOLOGIES LLC (US) 2022-08-03 EP claimed
CN-114729253-A Michael addition hardening synthetic resin for chemical fixing technology 费希尔厂有限责任两合公司 2022-07-08 CN claimed
CN-114729224-A Michael addition hardening hybrid system for chemical fixation technology 费希尔厂有限责任两合公司 2022-07-08 CN claimed
EP-4021998-A1 COATING COMPOSITION CURABLE BY ACETO-MICHAEL ADDITION BASF Coatings GmbH (DE) 2022-07-06 EP claimed
US-11370995-B2 Detergent additive DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-28 US claimed
US-20030073757-A1 Self-photoinitiating multifunctional acrylates ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC 2003-04-17 US claimed
WO-2003031502-A1 SELF-PHOTOINITIATING MULTIFUNCTIONAL ACRYLATES ASHLAND INC. (US) 2003-04-17 WO claimed
US-6342543-B1 Amine curable foundry binder system ASHLAND INC. 2002-01-29 US claimed
WO-2001021340-A1 AMINE CURABLE FOUNDRY BINDER SYSTEM ASHLAND INC. (US) 2001-03-29 WO claimed
WO-2001000684-A1 LIQUID OLIGOMERS CONTAINING UNSATURATION ASHLAND INC. (US) 2001-01-04 WO claimed
US-6025410-A WHICH CAN BE CROSSLINKED USING ULTRAVIOLET LIGHT WITHOUT ADDING COSTLY PHOTOINITATORS, PROTECTIVE OR DECORATIVE COATINGS, MICHAEL ADDITION REACTION OF ACETOACETATE FUNCTIONAL DONOR COMPOUNDS WITH MULTIFUNCTIONAL ACRYLATE RECEPTOR ASHLAND INC. (US) 2000-02-15 US claimed
US-5945489-A Liquid oligomers containing unsaturation ASHLAND, INC. (US) 1999-08-31 US claimed
WO-1996012579-A1 FOUNDRY MIXES AND THEIR USES ASHLAND INC. (US) 1996-05-02 WO claimed
US-5459178-A Aggregate and binder comprising an acetoacetate ester, di-or triacrylate and a liquid tertiary amine catalyst; foundry shapes made by no-bake process ASHLAND INC. (US) 1995-10-17 US claimed
US-5017649-A Low temperature crosslinking EASTMAN KODAK COMPANY (US) 1991-05-21 US claimed