SCHEMBL651229

SCHEMBL651229

CCC(COC(=O)CC(C)=O)(COC(=O)CC(C)=O)COC(=O)CC(C)=O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.46
GAA P10253 2/20 0.46
SI P14410 2/20 0.46
MGAM2 Q2M2H8 2/20 0.46
THRB P10828 1/20 0.38
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22050939 0.96 MGAM (0.46) MGAMGAASIMGAM2THRB
SCHEMBL22124844 0.94 THRB (0.42) MGAMGAASIMGAM2THRB
SCHEMBL23041383 0.91 DGKA (0.40) MGAMGAASIMGAM2THRB
SCHEMBL7708371 0.90 MGAM (0.41) MGAMGAASIMGAM2THRB
SCHEMBL8999875 0.90 MGAM (0.41) MGAMGAASIMGAM2THRB
SCHEMBL218916 0.89 MGAM (0.52) MGAMGAASIMGAM2ALDH1A1
SCHEMBL650457 0.85 MGAM (0.38) MGAMGAASIMGAM2THRB
SCHEMBL30914576 0.85 TSHR (0.42) ALDH1A1HSD17B10TDP1
SCHEMBL8999841 0.83 GAA (0.65) MGAMGAASIMGAM2THRB
SCHEMBL649062 0.83 MGAM (0.46) MGAMGAASIMGAM2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 582 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378434-B2 Curable coating compositions EASTMAN CHEMICAL COMPANY (US) 2025-08-05 US claimed
US-12187923-B2 Michael-addition-hardening synthetic resin for chemical fixing technology FISCHERWERKE GMBH & CO. KG (DE) 2025-01-07 US claimed
US-12180394-B2 Michael-addition-hardening hybrid system for chemical fixing technology FISCHERWERKE GMBH & CO. KG (DE) 2024-12-31 US claimed
WO-2024263666-A1 CURABLE COMPOSITIONS WITH LOW EXOTHERM HENKEL AG & CO. KGAA (DE) 2024-12-26 WO claimed
EP-3830157-B1 METHODS FOR REDUCING ALDEHYDE EMISSIONS IN POLYURETHANE FOAMS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-12-04 EP claimed
US-12077630-B2 Methods for reducing aldehyde emissions in polyurethane foams DOW GLOBAL TECHNOLOGIES LLC (US) 2024-09-03 US claimed
US-12037444-B2 Phenolic resin binder with reduced formaldehyde content ASK CHEMICALS GMBH (DE) 2024-07-16 US claimed
CN-113166033-B Curable coating composition 伊士曼化工公司 2024-05-24 CN claimed
US-11912832-B2 Organic-inorganic polymeric compositions, related articles, and related methods EASTERN MICHIGAN UNIVERSITY (US) 2024-02-27 US claimed
EP-3894386-B1 CURABLE COATING COMPOSITIONS EASTMAN CHEM CO (US) 2024-02-21 EP claimed
EP-0974610-B1 Curable epoxy compound and its use HILTI AG (LI) 2004-03-10 EP claimed
US-6673851-B2 COATING, ADHESIVE, LAMINATION; EXPOSURE TO ACTINIC LIGHT ASHLAND INC. 2004-01-06 US claimed
US-20030073757-A1 Self-photoinitiating multifunctional acrylates ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC 2003-04-17 US claimed
WO-2003031502-A1 SELF-PHOTOINITIATING MULTIFUNCTIONAL ACRYLATES ASHLAND INC. (US) 2003-04-17 WO claimed
US-6342543-B1 Amine curable foundry binder system ASHLAND INC. 2002-01-29 US claimed
WO-2001021340-A1 AMINE CURABLE FOUNDRY BINDER SYSTEM ASHLAND INC. (US) 2001-03-29 WO claimed
WO-1996012579-A1 FOUNDRY MIXES AND THEIR USES ASHLAND INC. (US) 1996-05-02 WO claimed
US-5459178-A Aggregate and binder comprising an acetoacetate ester, di-or triacrylate and a liquid tertiary amine catalyst; foundry shapes made by no-bake process ASHLAND INC. (US) 1995-10-17 US claimed
US-5017649-A Low temperature crosslinking EASTMAN KODAK COMPANY (US) 1991-05-21 US claimed
EP-0227454-A2 Crosslinked acetoacetic ester polymers COOK PAINT AND VARNISH INC. (US) 1987-07-01 EP claimed