SCHEMBL21891710

SCHEMBL21891710

O=C(O)Cc1ccccc1C(=O)N(C1CCCCC1)C1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
BCAT2 O15382 1/20 0.48
SLC6A2 P23975 7/20 0.47
SLC6A4 P31645 7/20 0.47
SLC6A3 Q01959 2/20 0.47
KCNH2 Q12809 2/20 0.47
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
RECQL P46063 1/20 0.46
ADAM17 P78536 1/20 0.46
S1PR1 P21453 1/20 0.45
S1PR3 Q99500 1/20 0.45
TRPM8 Q7Z2W7 2/20 0.44
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21891520 0.86 HPGD (0.62) LMNAMAPTBCAT2KMT2AMEN1
SCHEMBL9812817 0.82 SLC6A2 (0.57) LMNAMAPTHTTNPSR1SLC6A2
SCHEMBL2363287 0.81 SLC6A2 (0.53) LMNAMAPTHTTNPSR1SLC6A2
SCHEMBL21886445 0.80 SLC6A2 (0.52) LMNAMAPTHTTNPSR1SLC6A2
SCHEMBL15807707 0.75 SLC6A2 (0.51) LMNAMAPTHTTNPSR1SLC6A2
SCHEMBL29589341 0.75 SLC6A2 (0.51) LMNAMAPTHTTNPSR1SLC6A2
SCHEMBL28414939 0.75 SLC6A2 (0.51) LMNAMAPTHTTNPSR1SLC6A2
SCHEMBL15138843 0.75 SLC6A2 (0.51) LMNAMAPTHTTNPSR1SLC6A2
SCHEMBL1004218 0.74 LMNA (0.65) LMNAMAPTHTTNPSR1SLC6A2
SCHEMBL9542128 0.73 LMNA (0.51) LMNASLC6A2SLC6A4SLC6A3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020054226-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, LAMINATE, METHOD FOR PRODUCING CURED FILM, AND SEMICONDUCTOR DEVICE 富士フイルム株式会社 2020-03-19 WO disclosed