Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18106013 | 0.86 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDTRPM8GAA | |
| SCHEMBL21892001 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDTRPM8GAA | |
| SCHEMBL21892018 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDTRPM8GAA | |
| SCHEMBL16710296 | 0.78 | ELANE (0.71) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL21892004 | 0.76 | KDM4E (0.55) | ALDH1A1KDM4EHPGDTRPM8GAA | |
| SCHEMBL34468091 | 0.75 | KDM4E (0.72) | ALDH1A1KDM4EHPGDTRPM8GAA | |
| SCHEMBL3565700 | 0.75 | KDM4E (0.72) | ALDH1A1KDM4EHPGDTRPM8GAA | |
| SCHEMBL3565699 | 0.75 | KDM4E (0.72) | ALDH1A1KDM4EHPGDTRPM8GAA | |
| SCHEMBL2486592 | 0.73 | KDM4E (1.00) | ALDH1A1KDM4EHPGDTRPM8GAA | |
| SCHEMBL2486594 | 0.73 | KDM4E (1.00) | ALDH1A1KDM4EHPGDTRPM8GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10624943-B2 | Kava derived therapeutic compounds and methods of use thereof | Kuality Herbceutics, LLC (US) | 2020-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10624943-B2 | Kava derived therapeutic compounds and methods of use thereof | KLK5, KLK4, KLK2 | ALDH1A1 1649/4885KDM4E 90/4885HPGD 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.