Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3565699 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL34468091 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL11014364 | 0.92 | KDM4E (0.62) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL12499737 | 0.92 | KDM4E (0.62) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL10733556 | 0.91 | MAOB (0.71) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL10733568 | 0.91 | MAOB (0.71) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL11698809 | 0.87 | ALDH1A1 (0.67) | KDM4EALDH1A1GAAHPGDTRPM8 | |
| SCHEMBL24419913 | 0.86 | KDM4E (0.54) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL17639928 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1GAAHPGDMAPT | |
| SCHEMBL24419743 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1GAAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11533912-B2 | Use of cinnamate compounds in the control of fungal diseases of crops | INSTITUTE OF PLANT PROTECTION, GANSU ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2022-12-27 | — | — | US | claimed |
| US-20210137110-A1 | USE OF CINNAMATE COMPOUNDS IN THE CONTROL OF FUNGAL DISEASES OF CROPS | INSTITUTE OF PLANT PROTECTION, GANSU ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2021-05-13 | — | — | US | claimed |
| US-20260028340-A1 | SUBSTITUTED DERIVATIVES OF ISOINDOLES | SUPERNUS PHARMACEUTICALS, INC. (US) | 2026-01-29 | — | — | US | disclosed |
| US-12454535-B2 | Substituted derivatives of isoindoles | SUPERNUS PHARMACEUTICALS, INC. (US) | 2025-10-28 | — | — | US | disclosed |
| US-20250197412-A1 | SUBSTITUTED DERIVATIVES OF ISOINDOLES | SUPERNUS PHARMACEUTICALS, INC. (US) | 2025-06-19 | — | — | US | disclosed |
| US-11533912-B2 | Use of cinnamate compounds in the control of fungal diseases of crops | INSTITUTE OF PLANT PROTECTION, GANSU ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2022-12-27 | — | — | US | disclosed |
| US-20210137110-A1 | USE OF CINNAMATE COMPOUNDS IN THE CONTROL OF FUNGAL DISEASES OF CROPS | INSTITUTE OF PLANT PROTECTION, GANSU ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2021-05-13 | — | — | US | disclosed |
| US-7825256-B2 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| US-7825256-B2 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| EP-1817030-A2 | INDUCIBLE NITRIC OXIDE SYNTHASE DIMERIZATION INHIBITORS | Kalypsys, Inc. (US) | 2007-08-15 | — | — | EP | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |
| WO-2006060424-A2 | INDUCIBLE NITRIC OXIDE SYNTHASE DIMERIZATION INHIBITORS | KALYPSYS, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
| US-20060116515-A1 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. | 2006-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028340-A1 | SUBSTITUTED DERIVATIVES OF ISOINDOLES | ADRB3, ADRB2, SLC6A3 | KDM4E 3546/4885ALDH1A1 597/4885GAA 2395/4885 |
| US-20060116515-A1 | Inducible nitric oxide synthase dimerization inhibitors | NOS3, NOS2, NOS1 | KDM4E 1567/4885ALDH1A1 2795/4885GAA 4162/4885 |
| US-12454535-B2 | Substituted derivatives of isoindoles | TPH2, CYP11B2, CYP3A5 | KDM4E 3804/4885ALDH1A1 203/4885GAA 2058/4885 |
| US-20250197412-A1 | SUBSTITUTED DERIVATIVES OF ISOINDOLES | OPRK1, TPH2, NLN | KDM4E 4394/4885ALDH1A1 592/4885GAA 1630/4885 |
| US-20210137110-A1 | USE OF CINNAMATE COMPOUNDS IN THE CONTROL OF FUNGAL DISEASES OF CROPS | CROCC, GNMT, KDM3A | KDM4E 23/4885ALDH1A1 2863/4885GAA 242/4885 |
| US-11533912-B2 | Use of cinnamate compounds in the control of fungal diseases of crops | CROCC, GNMT, KDM3A | KDM4E 23/4885ALDH1A1 2863/4885GAA 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.