Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.49 |
| ▸ | MGLL | Q99685 | 15/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893717 | 0.90 | P2RX7 (0.46) | P2RX7MGLLHPGDNAMPT | |
| SCHEMBL21893734 | 0.90 | MGLL (0.46) | P2RX7MGLL | |
| SCHEMBL21893738 | 0.89 | P2RX7 (0.50) | P2RX7MGLL | |
| SCHEMBL21894024 | 0.89 | MGLL (0.47) | P2RX7MGLLHPGDNAMPT | |
| SCHEMBL21818705 | 0.89 | MGLL (0.56) | P2RX7MGLL | |
| SCHEMBL23872204 | 0.88 | P2RX7 (0.47) | P2RX7MGLLNAMPT | |
| SCHEMBL21894043 | 0.87 | MGLL (0.50) | P2RX7MGLL | |
| SCHEMBL21818432 | 0.87 | MGLL (0.59) | P2RX7MGLL | |
| SCHEMBL21819385 | 0.87 | MGLL (0.58) | P2RX7MGLLNAMPT | |
| SCHEMBL21893493 | 0.87 | MGLL (0.58) | P2RX7MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |