Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893925 | 0.87 | PDE4B (0.39) | HTR2CHTR2AHTR2BHTR6 | |
| SCHEMBL21894372 | 0.86 | CD274 (0.45) | HTR2CHTR2AHTR2BHTR6 | |
| SCHEMBL21893457 | 0.83 | HTR2A (0.41) | HTR2CHTR2AHTR2B | |
| SCHEMBL21893446 | 0.83 | ASIC3 (0.49) | HTR2CHTR2AHTR2B | |
| SCHEMBL21818995 | 0.81 | HTR7 (0.48) | HTR2CHTR2AHTR2B | |
| SCHEMBL29935808 | 0.79 | HTR7 (0.49) | HTR2CHTR2AHTR2B | |
| SCHEMBL21819177 | 0.78 | KCNH2 (0.41) | HTR2CHTR2AHTR2BDYRK1ACLK2 | |
| SCHEMBL21819180 | 0.78 | KCNH2 (0.41) | HTR2CHTR2AHTR2BDYRK1ACLK2 | |
| SCHEMBL31133389 | 0.78 | KCNH2 (0.41) | HTR2CHTR2AHTR2BDYRK1ACLK2 | |
| SCHEMBL21818664 | 0.78 | HTR2C (0.56) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |