Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.59 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893503 | 0.91 | MGLL (0.56) | MGLLP2RX7DPP4DPP8DPP7 | |
| SCHEMBL21893816 | 0.86 | MGLL (0.52) | MGLLP2RX7 | |
| SCHEMBL21893992 | 0.82 | MGLL (0.55) | MGLLP2RX7 | |
| SCHEMBL21818446 | 0.81 | MGLL (0.64) | MGLL | |
| SCHEMBL21818448 | 0.81 | MGLL (0.64) | MGLL | |
| SCHEMBL21893986 | 0.80 | MGLL (0.56) | MGLLP2RX7DPP4DPP8DPP7 | |
| SCHEMBL21894457 | 0.80 | MGLL (0.48) | MGLLP2RX7DPP4DPP8DPP7 | |
| SCHEMBL21894461 | 0.79 | P2RX7 (0.46) | MGLLP2RX7 | |
| SCHEMBL21893950 | 0.79 | MGLL (0.60) | MGLLP2RX7 | |
| SCHEMBL21893860 | 0.79 | MGLL (0.58) | MGLLP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |