⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL6564019 | 0.95 | SHBG (0.31) | — | |
| Formaldehyde SCHEMBL9538247 | 0.92 | — | — | |
| Acrylic Acid SCHEMBL8676757 | 0.79 | LMNA (0.37) | — | |
| SCHEMBL22027537 | 0.69 | — | — | |
| SCHEMBL1668637 | 0.69 | CNR2 (0.36) | — | |
| SCHEMBL24052379 | 0.66 | CNR2 (0.35) | — | |
| SCHEMBL24052391 | 0.66 | CNR2 (0.35) | — | |
| SCHEMBL11771376 | 0.66 | CNR2 (0.35) | — | |
| SCHEMBL24052123 | 0.66 | — | — | |
| SCHEMBL6507028 | 0.66 | CNR2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605001-B2 | Production of polyketides and other natural products | BUCK INSTITUTE FOR RESEARCH ON AGING (US) | 2017-03-28 | — | — | US | disclosed |
| US-20150266896-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | BIOTICA TECH LTD (GB) | 2015-09-24 | — | — | US | disclosed |
| US-9040259-B2 | Production of polyketides and other natural products | BUCK INSTITUTE FOR RESEARCH ON AGING (US) | 2015-05-26 | — | — | US | disclosed |
| US-20110165633-A1 | Production of Polyketides and Other Natural Products | BUCK INSTITUTE FOR RESEARCH ON AGING | 2011-07-07 | — | — | US | disclosed |
| US-7645768-B2 | Production of polyketides and other natural products | WYETH (US) | 2010-01-12 | — | — | US | disclosed |
| US-20080287482-A1 | Production of Polyketides and Other Natural Products | GREGORY MATTHEW ALAN | 2008-11-20 | — | — | US | disclosed |
| US-7390895-B2 | Production of polyketides and other natural products | BIOTICA TECHNOLOGY LIMITED (GB) | 2008-06-24 | — | — | US | disclosed |
| US-20080039486-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | GREGORY MATTHEW A | 2008-02-14 | — | — | US | disclosed |
| US-20080021211-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | BIOTICA TECHNOLOGY LIMITED (GB) | 2008-01-24 | — | — | US | disclosed |
| US-7300942-B2 | Production of polyketides and other natural products | BIOTICA TECHNOLOGY LIMITED (GB) | 2007-11-27 | — | — | US | disclosed |
| US-20060078980-A1 | Production of polyketides and other natural products | GREGORY MATTHEW A | 2006-04-13 | — | — | US | disclosed |
| US-20050272132-A1 | Production of polyketides and other natural products | BIOTICA TECHNOLOGY LIMITED (GB) | 2005-12-08 | — | — | US | disclosed |