Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240375 | 0.82 | HSD17B10 (0.44) | HSD17B10ALDH1A1HTTKMT2AGAA | |
| SCHEMBL2169693 | 0.66 | ITGB1 (0.42) | ALDH1A1HTTKMT2AHPGDMEN1 | |
| SCHEMBL2172271 | 0.66 | KDM4E (0.39) | HSD17B10ALDH1A1HTTKMT2AGAA | |
| SCHEMBL2170645 | 0.65 | GAA (0.45) | ALDH1A1GAALMNAUSP2HCRTR2 | |
| SCHEMBL2168643 | 0.65 | USP2 (0.36) | ALDH1A1GAAUSP2 | |
| SCHEMBL2170385 | 0.65 | P2RX7 (0.39) | KMT2AGAAMEN1USP2 | |
| SCHEMBL2170594 | 0.65 | USP2 (0.36) | HSD17B10ALDH1A1GAAPREPUSP2 | |
| SCHEMBL2169957 | 0.65 | EPHX2 (0.39) | ALDH1A1HTTKMT2AMEN1USP2 | |
| SCHEMBL2169493 | 0.65 | HTT (0.50) | HSD17B10ALDH1A1HTTKMT2AGAA | |
| SCHEMBL2168761 | 0.64 | HCRTR1 (0.37) | HSD17B10ALDH1A1KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348019-A1 | 1,2-DIAZETIDIN-3-ONE DERIVATIVE AND PHARMACEUTICAL AGENT COMPRISING SAME | Kowa Company, Ltd. (JP) | 2011-07-27 | — | — | EP | claimed |
| EP-2348019-A1 | 1,2-DIAZETIDIN-3-ONE DERIVATIVE AND PHARMACEUTICAL AGENT COMPRISING SAME | Kowa Company, Ltd. (JP) | 2011-07-27 | — | — | EP | disclosed |