SCHEMBL2170385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2169415	0.89	P2RX7 (0.36)	P2RX7USP2EPHX2
	SCHEMBL2169693	0.87	ITGB1 (0.42)	P2RX7KMT2AUSP2MEN1ELANE
	SCHEMBL2172271	0.87	KDM4E (0.39)	RAB9AKMT2AUSP2MEN1GAA
	SCHEMBL2169337	0.87	EPHX2 (0.39)	P2RX7KMT2AUSP2MEN1EPHX2
	SCHEMBL2171870	0.86	TP53 (0.41)	P2RX7TP53
	SCHEMBL2169004	0.86	P2RX7 (0.40)	P2RX7RAB9AKMT2AUSP2MEN1
	SCHEMBL2169957	0.86	EPHX2 (0.39)	RAB9ATP53KMT2AUSP2MEN1
	SCHEMBL2170645	0.86	GAA (0.45)	P2RX7USP2ELANEGAA
	SCHEMBL2168643	0.86	USP2 (0.36)	USP2CNR2GAAEPHX2
	SCHEMBL2170594	0.86	USP2 (0.36)	RAB9AUSP2GAAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.