⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713274 | 0.86 | KDM4A (0.42) | — | |
| SCHEMBL17721372 | 0.84 | — | — | |
| SCHEMBL29736409 | 0.82 | PRMT3 (0.36) | — | |
| SCHEMBL25415513 | 0.82 | CYP2C9 (0.37) | — | |
| SCHEMBL27467974 | 0.82 | PRMT3 (0.50) | — | |
| SCHEMBL13936327 | 0.80 | PRMT3 (0.48) | — | |
| SCHEMBL179678 | 0.80 | — | — | |
| SCHEMBL23728803 | 0.79 | KDM4C (0.38) | — | |
| SCHEMBL23730577 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL19924993 | 0.78 | PRMT3 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462594-A | Pradienolide compound and application thereof | 卫材R&D管理有限公司 | 2025-02-18 | — | — | CN | claimed |
| EP-3642198-B1 | SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LTD (GB) | 2022-03-16 | — | — | EP | claimed |
| EP-2914600-A2 | FUNCTIONALIZED 9-BROMO-CAMPTOTHECIN DERIVATIVES | Nerviano Medical Sciences S.r.l. (IT) | 2015-09-09 | — | — | EP | claimed |
| WO-2014067960-A9 | FUNCTIONALIZED 9-BROMO-CAMPTOTHECIN DERIVATIVES | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-07-09 | — | — | WO | claimed |
| WO-2014067960-A2 | FUNCTIONALIZED 9-BROMO-CAMPTOTHECIN DERIVATIVES | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2014-05-08 | — | — | WO | claimed |
| EP-1549655-B1 | SUBSTITUTED BICYCLIC THIOPHENE DERIVATIVES, COMPOSTIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2009-01-21 | — | — | EP | claimed |
| US-20050239865-A1 | Substituted bicyclic thiophene derivatives, compositions containing such compounds and methods of use | MERCK SHARP & DOHME CORP. | 2005-10-27 | — | — | US | claimed |
| US-20250288606-A1 | POLYMER-CONJUGATED METAP2 INHIBITORS, AND THERAPEUTIC METHODS OF USE THEREOF | SYNDEVRX, INC. | 2025-09-18 | — | — | US | disclosed |
| CN-119462594-A | Pradienolide compound and application thereof | 卫材R&D管理有限公司 | 2025-02-18 | — | — | CN | disclosed |
| US-20250019377-A1 | 1, 4-OXAZEPANE DERIVATIVES AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2025-01-16 | — | — | US | disclosed |
| EP-4398942-A1 | LINKERS FOR USE IN ANTIBODY DRUG CONJUGATES | Orum Therapeutics Inc. (KR) | 2024-07-17 | — | — | EP | disclosed |
| US-12037378-B2 | Variant CD58 domains and uses thereof | NOVARTIS AG (CH) | 2024-07-16 | — | — | US | disclosed |
| US-20240182441-A1 | 2-(2,4,5-SUBSTITUTED-ANILINO)PYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2024-06-06 | — | — | US | disclosed |
| CN-100439371-C | 5, 7-diaminopyrazolo [4, 3-d ] pyrimidines useful in the treatment of hypertension | PFIZER LTD (GB) | 2008-12-03 | — | — | CN | disclosed |
| US-20070270412-A1 | NOVEL PHARMACEUTICALS | PFIZER INC | 2007-11-22 | — | — | US | disclosed |
| US-7262192-B2 | Substituted pyrazolo[4,3-d]pyrimidines and their use as PDE-5 inhibitors | PFIZER INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-20050043325-A1 | Novel pharmaceuticals | PFIZER INC | 2005-02-24 | — | — | US | disclosed |
| US-6479515-B1 | FOR THE TREATMENT OF PAIN AND INFLAMMATION, AND ESPECIALLY IN THE TREATMENT OF ASTHMA, CEREBRAL TRAUMATIC SHOCK AND ALLERGIC RHINITIS | FOURNIER INDUSTRIE ET SANTE (FR) | 2002-11-12 | — | — | US | disclosed |
| EP-0634996-A1 | 1,4 NAPHTHOQUINONE DERIVTIVES WITH ANTI-PROTOZOAL AND ANTI-PARASITIC ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-01-25 | — | — | EP | disclosed |
| CN-1083048-A | Heterogeneous ring compound | WELLCOME FOUND (GB) | 1994-03-02 | — | — | CN | disclosed |