Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 4/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713274 | 0.92 | KDM4A (0.42) | KDM4CKDM4AHDAC1PRMT3CARM1 | |
| SCHEMBL10045279 | 0.81 | PRMT3 (0.48) | KDM4CKDM4AS1PR2S1PR1S1PR3 | |
| SCHEMBL2189591 | 0.79 | — | — | |
| SCHEMBL1231390 | 0.78 | PRMT3 (0.50) | KDM4CKDM4AS1PR2S1PR1S1PR3 | |
| SCHEMBL28903229 | 0.78 | NOS3 (0.38) | APP | |
| SCHEMBL910571 | 0.78 | EPHX1 (0.54) | KDM4CKDM4AS1PR2S1PR1S1PR3 | |
| SCHEMBL29300379 | 0.78 | KISS1R (0.36) | KDM4CKDM4AS1PR2S1PR1S1PR3 | |
| SCHEMBL23728793 | 0.76 | CA14 (0.41) | HDAC1 | |
| SCHEMBL469832 | 0.76 | PRMT3 (0.48) | KDM4CKDM4AS1PR2S1PR1S1PR3 | |
| SCHEMBL16317337 | 0.76 | PRMT3 (0.48) | KDM4CKDM4AS1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100404-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021158707-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2021-08-12 | — | — | WO | disclosed |