Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.52 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.52 |
| ▸ | DTYMK | P23919 | 4/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323932 | 0.82 | DTYMK (0.55) | POLBENPP1P2RY1DTYMKDNPH1 | |
| SCHEMBL29330468 | 0.82 | DTYMK (0.55) | POLBENPP1P2RY1DTYMKDNPH1 | |
| SCHEMBL10034046 | 0.80 | POLB (0.66) | POLBENPP1P2RY1DTYMKNT5E | |
| SCHEMBL21896065 | 0.80 | DTYMK (0.40) | POLBENPP1P2RY1DTYMKTRPM2 | |
| SCHEMBL21896050 | 0.79 | DTYMK (0.47) | POLBENPP1P2RY1DTYMKDNPH1 | |
| SCHEMBL23679569 | 0.79 | POLB (0.49) | POLBENPP1P2RY1DTYMKTRPM2 | |
| SCHEMBL8979286 | 0.79 | POLB (0.53) | POLBENPP1P2RY1DTYMKTRPM2 | |
| SCHEMBL16871807 | 0.79 | POLB (0.53) | POLBENPP1P2RY1DTYMKTRPM2 | |
| SCHEMBL19069603 | 0.78 | DTYMK (0.68) | POLBENPP1P2RY1DTYMKTERT | |
| SCHEMBL16743928 | 0.78 | DTYMK (0.68) | POLBENPP1P2RY1DTYMKTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020057546-A1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | 上海迪诺医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |