Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060296 | 0.77 | KMT2A (0.33) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL13054420 | 0.75 | GABRA1 (0.38) | PTGS1PTGS2ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL22607369 | 0.75 | PTGS1 (0.38) | PTGS1PTGS2KMT2AKDM4EMEN1 | |
| SCHEMBL26005534 | 0.74 | PTGS1 (0.37) | PTGS1PTGS2SMN1; SMN2MAPT | |
| SCHEMBL12412397 | 0.74 | PTGS1 (0.37) | PTGS1PTGS2SMN1; SMN2LMNAMAPT | |
| SCHEMBL13303318 | 0.74 | GABRA1 (0.41) | PTGS1PTGS2KDM4EALDH1A1GAA | |
| SCHEMBL21371871 | 0.73 | RAB9A (0.34) | SCN5ASCN9ANPC1RAB9AKMT2A | |
| SCHEMBL13085692 | 0.71 | PLK1 (0.50) | PTGS1PTGS2NPC1RAB9AKDM4E | |
| SCHEMBL17127617 | 0.71 | PTGS1 (0.38) | PTGS1PTGS2KMT2AKDM4EMEN1 | |
| SCHEMBL801439 | 0.70 | PTGS1 (0.34) | PTGS1PTGS2KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3639824-A1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS FOR TREATING NEISSERIA GONORRHOEA INFECTION | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2020-04-22 | — | — | EP | disclosed |