Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21754322 | 0.78 | TLR7 (0.40) | TLR7 | |
| SCHEMBL20780662 | 0.71 | CCR1 (0.45) | — | |
| SCHEMBL30493685 | 0.70 | CYP1A2 (0.54) | — | |
| SCHEMBL23348864 | 0.70 | HCAR2 (0.45) | PIM1 | |
| SCHEMBL30579323 | 0.69 | CDK2 (0.53) | TLR7 | |
| SCHEMBL26638142 | 0.69 | NQO2 (0.35) | TLR7 | |
| SCHEMBL30493780 | 0.69 | NQO2 (0.35) | TLR7 | |
| SCHEMBL20839320 | 0.68 | PIK3CA (0.39) | TLR7PIM1 | |
| SCHEMBL29856247 | 0.68 | PIK3CA (0.39) | TLR7PIM1 | |
| SCHEMBL18194358 | 0.66 | KDM4E (0.39) | PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081636-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2020-04-23 | — | — | WO | disclosed |