SCHEMBL29856247

SCHEMBL29856247

Cc1nc(-c2cncc(F)c2)ncc1N

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 6/20 0.39
CYP11B2 P19099 4/20 0.38
CYP11B1 P15538 3/20 0.38
PIM1 P11309 1/20 0.38
NQO2 P16083 1/20 0.36
ADORA2B P29275 1/20 0.36
TLR7 Q9NYK1 6/20 0.35
CYP19A1 P11511 1/20 0.33
ADRA2B P18089 1/20 0.33
PIK3R1 P27986 1/20 0.33
MTOR P42345 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20839320 1.00 PIK3CA (0.39) PIK3CACYP11B2CYP11B1PIM1NQO2
SCHEMBL20849498 0.83 CYP2A6 (0.38) PIK3CACYP11B2CYP11B1TLR7
SCHEMBL20839258 0.81 CYP11B2 (0.43) CYP11B2CYP11B1
SCHEMBL29856016 0.81 CYP11B2 (0.43) CYP11B2CYP11B1
SCHEMBL25703918 0.79 CYP11B2 (0.36) PIK3CACYP11B2CYP11B1PIM1NQO2
SCHEMBL20839164 0.78 NQO2 (0.34) PIK3CACYP11B2CYP11B1PIM1NQO2
SCHEMBL29855887 0.78 NQO2 (0.34) PIK3CACYP11B2CYP11B1PIM1NQO2
SCHEMBL29855842 0.78 CYP11B2 (0.36) PIK3CACYP11B2CYP11B1PIM1TLR7
SCHEMBL20839319 0.78 CYP11B2 (0.36) PIK3CACYP11B2CYP11B1PIM1TLR7
SCHEMBL20839157 0.78 ADK (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111372455-B Herbicidally active pyridyl-/pyrimidinyl-pyrimidine derivatives 先正达参股股份有限公司 2022-10-11 CN disclosed