Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856247 | 1.00 | PIK3CA (0.39) | PIK3CACYP11B2CYP11B1PIM1NQO2 | |
| SCHEMBL20849498 | 0.83 | CYP2A6 (0.38) | PIK3CACYP11B2CYP11B1TLR7 | |
| SCHEMBL20839258 | 0.81 | CYP11B2 (0.43) | CYP11B2CYP11B1 | |
| SCHEMBL29856016 | 0.81 | CYP11B2 (0.43) | CYP11B2CYP11B1 | |
| SCHEMBL25703918 | 0.79 | CYP11B2 (0.36) | PIK3CACYP11B2CYP11B1PIM1NQO2 | |
| SCHEMBL20839164 | 0.78 | NQO2 (0.34) | PIK3CACYP11B2CYP11B1PIM1NQO2 | |
| SCHEMBL29855887 | 0.78 | NQO2 (0.34) | PIK3CACYP11B2CYP11B1PIM1NQO2 | |
| SCHEMBL29855842 | 0.78 | CYP11B2 (0.36) | PIK3CACYP11B2CYP11B1PIM1TLR7 | |
| SCHEMBL20839319 | 0.78 | CYP11B2 (0.36) | PIK3CACYP11B2CYP11B1PIM1TLR7 | |
| SCHEMBL20839157 | 0.78 | ADK (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11672251-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrimidine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-13 | — | — | US | disclosed |
| US-11672251-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrimidine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-13 | — | — | US | disclosed |
| US-11672251-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrimidine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-13 | — | — | US | disclosed |
| EP-3684182-B1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3684182-B1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| CN-111372455-B | Herbicidally active pyridyl-/pyrimidinyl-pyrimidine derivatives | 先正达参股股份有限公司 | 2022-10-11 | — | — | CN | disclosed |
| US-20200267981-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrimidine Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| US-20200267981-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrimidine Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| EP-3684182-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRIMIDINE DERIVATIVES | Syngenta Participations AG (CH) | 2020-07-29 | — | — | EP | disclosed |
| CN-111372455-A | Herbicidally active pyridyl-/pyrimidinyl-pyrimidine derivatives | 先正达参股股份有限公司 | 2020-07-03 | — | — | CN | disclosed |
| WO-2019057720-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
| WO-2019057720-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200267981-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrimidine Derivatives | PLPBP, PDXK, DPYD | PIK3CA 655/4885CYP11B2 2262/4885CYP11B1 2113/4885 |
| US-11672251-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrimidine derivatives | PLPBP, PDXK, DPYD | PIK3CA 655/4885CYP11B2 2262/4885CYP11B1 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.